Apoquel (Oclacitinib) Dosage for Dogs
This dosage information is for educational purposes only. Always consult your veterinarian before giving any medication to your pet. Dosages may vary based on your pet's health conditions, other medications, and individual factors.
Dosage Calculator
Enter your dog's weight to calculate the recommended dose.
Recommended Dosage
Low Dose
—
mg
Standard Dose
—
mg
Max Dose
—
mg
Frequency
twice daily for 14 days, then once daily
These calculations are estimates based on standard veterinary dosing guidelines. Always confirm with your veterinarian before administering medication.
Apoquel Dosage Chart for Dogs by Weight
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| Weight | Low Dose | Standard Dose | Max Dose | Frequency |
|---|---|---|---|---|
| 5 lbs (2.3 kg) | 1mg | 1.5mg | 1.5mg | twice daily for 14 days, then once daily |
| 10 lbs (4.5 kg) | 2mg | 2.5mg | 2.5mg | twice daily for 14 days, then once daily |
| 15 lbs (6.8 kg) | 2.5mg | 4mg (3.6mg tablet) | 4mg (3.6mg tablet) | twice daily for 14 days, then once daily |
| 20 lbs (9.1 kg) | 3.5mg (3.6mg tablet) | 5.5mg | 5.5mg | twice daily for 14 days, then once daily |
| 25 lbs (11.3 kg) | 4.5mg | 7mg (2 × 3.6mg) | 7mg (2 × 3.6mg) | twice daily for 14 days, then once daily |
| 30 lbs (13.6 kg) | 5.5mg | 8mg (2 × 3.6mg) | 8mg (2 × 3.6mg) | twice daily for 14 days, then once daily |
| 40 lbs (18.1 kg) | 7mg (2 × 3.6mg) | 11mg (3 × 3.6mg) | 11mg (3 × 3.6mg) | twice daily for 14 days, then once daily |
| 50 lbs (22.7 kg) | 9mg | 13.5mg (4 × 3.6mg) | 13.5mg (4 × 3.6mg) | twice daily for 14 days, then once daily |
| 60 lbs (27.2 kg) | 11mg (3 × 3.6mg) | 16.5mg | 16.5mg | twice daily for 14 days, then once daily |
| 70 lbs (31.7 kg) | 12.5mg | 19mg | 19mg | twice daily for 14 days, then once daily |
| 80 lbs (36.3 kg) | 14.5mg (4 × 3.6mg) | 22mg (6 × 3.6mg) | 22mg (6 × 3.6mg) | twice daily for 14 days, then once daily |
| 90 lbs (40.8 kg) | 16.5mg | 24.5mg (7 × 3.6mg) | 24.5mg (7 × 3.6mg) | twice daily for 14 days, then once daily |
| 100 lbs (45.4 kg) | 18mg (5 × 3.6mg) | 27mg | 27mg | twice daily for 14 days, then once daily |
| 120 lbs (54.4 kg) | 22mg (6 × 3.6mg) | 32.5mg (9 × 3.6mg) | 32.5mg (9 × 3.6mg) | twice daily for 14 days, then once daily |
| 150 lbs (68 kg) | 27mg | 41mg | 41mg | twice daily for 14 days, then once daily |
What is Apoquel (Oclacitinib) used for in dogs?
How to give Apoquel to your dog
Apoquel can be given with or without food. For the first 14 days, give twice daily to achieve faster itch control, then reduce to once daily for maintenance. Do not break or split tablets. Apoquel is prescription-only — your vet will determine the appropriate tablet size based on your dog's weight.
Available Forms
tablet
Give with Food?
No — can be given without food
Side effects of Apoquel in dogs
Common side effects
Serious side effects
- increased susceptibility to infections
- skin lumps or masses
- bone marrow suppression
- increased risk of neoplasia with long-term use
When to call the vet
Call your vet immediately if your dog shows any of these signs:
- New lumps or skin masses develop
- Signs of infection (fever, lethargy, coughing)
- Persistent vomiting or diarrhea
- Severe lethargy or appetite loss
- Itching does not improve within 2 weeks