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Macrocyclic Lactone Antiparasitic · For Cats

Ivermectin dosage reference for cats (Heartgard)

This page's standard weight-based reference is 0.2 mg per kg (0.09 mg per lb), with Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention recorded as the reference frequency. Use the calculator to see the arithmetic for your cat's weight, then confirm the indication, product, and actual dose with a veterinarian.

Onset
4-8 hours
Duration
Varies by parasite; heartworm prevention lasts approximately 30 days
Class
Macrocyclic Lactone Antiparasitic

Weight-based calculator estimate from the references listed on this page. This page has not been independently DVM-reviewed — see our methodology .

This information is for educational purposes only. Always consult your veterinarian before giving medication to your pet. Do not use this calculator for emergencies, overdoses, pregnancy, very young animals, very old animals, pets with liver/kidney disease, or pets taking multiple medications.

Each medication page lists the references recorded for its data. The calculator math and editorial presentation are maintained by PetDosageChart; a page is independently DVM-reviewed only when a named reviewer byline appears. See our methodology and limitations.

Ivermectin (often known by brand names such as Heartgard, Ivomec, and Acarexx (otic)) is a macrocyclic lactone antiparasitic commonly used in veterinary medicine for Ear mite treatment (Otodectes cynotis), Heartworm prevention, Intestinal parasite treatment, Demodectic mange (off-label), and Notoedric mange (off-label). Understanding the correct dosage, administration, and potential side effects of Ivermectin is critical for your cat’s safety and well-being.

A typical Ivermectin dose for cats is around 0.2 mg/kg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention, within a usual range of 0.024-0.4 mg/kg. Available forms include Injectable solution (used orally or by injection), Topical (otic), and Oral paste.

Calculator Warning: Use this only as an educational estimate. Your veterinarian may prescribe a different dose based on your pet’s condition, age, weight, other medications, and medical history.

Ivermectin Dosage Calculator for Cats

Enter your cat’s weight below to estimate the Ivermectin dose from the 0.2 mg/kg guideline. Your veterinarian may adjust it for your cat’s age, condition, and other medications, so treat the result as an educational starting point, not a prescription.

Dosage Calculator · 01

Enter your cat's weight

Quick Dosage Chart

Typical Ivermectin amounts for common cat weights, for quick reference:

Dosage Chart · 02

Heartgard weight-based reference chart for cats

Scroll sideways to see full table

Weight Lower Reference Standard Reference Upper Reference Frequency
3 lbs (1.4 kg) 0.034 mg 0.28 mg (4 × 0.068mg) 0.56 mg (8 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
4 lbs (1.8 kg) 0.043 mg 0.36 mg 0.72 mg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
5 lbs (2.3 kg) 0.055 mg (0.068mg tablet) 0.46 mg (7 × 0.068mg) 0.92 mg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
6 lbs (2.7 kg) 0.065 mg (0.068mg tablet) 0.54 mg (8 × 0.068mg) 1.1 mg (16 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
7 lbs (3.2 kg) 0.077 mg (0.068mg tablet) 0.64 mg 1.3 mg (19 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
8 lbs (3.6 kg) 0.086 mg 0.72 mg 1.4 mg (21 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
9 lbs (4.1 kg) 0.098 mg 0.82 mg (12 × 0.068mg) 1.6 mg (24 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
10 lbs (4.5 kg) 0.11 mg 0.90 mg (13 × 0.068mg) 1.8 mg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
12 lbs (5.4 kg) 0.13 mg (2 × 0.068mg) 1.1 mg (16 × 0.068mg) 2.2 mg (32 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
14 lbs (6.3 kg) 0.15 mg (2 × 0.068mg) 1.3 mg 2.5 mg (37 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
16 lbs (7.3 kg) 0.18 mg 1.5 mg 2.9 mg (43 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
18 lbs (8.2 kg) 0.20 mg (3 × 0.068mg) 1.6 mg (24 × 0.068mg) 3.3 mg (48 × 0.068mg) Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
20 lbs (9.1 kg) 0.22 mg (3 × 0.068mg) 1.8 mg (27 × 0.068mg) 3.6 mg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention
25 lbs (11.3 kg) 0.27 mg (4 × 0.068mg) 2.3 mg (33 × 0.068mg) 4.5 mg Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention

Parenthetical tablet amounts are arithmetic comparisons only. They do not account for scoring, release type, concentration, product labeling, or whether this medication is appropriate for an individual animal.

By Weight

Heartgard reference by cat weight

Choose a common weight to open its optional reference page. Use the main medication calculator for a different exact weight.

Common-weight pages are convenience views of the same educational reference, not separate medical recommendations.

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One Ivermectin Number Cannot Cover Every Use

This page’s record spans a wide 0.024–0.4 mg/kg range and uses 0.2 mg/kg as its standard arithmetic reference. That alone shows why weight is not enough: heartworm prevention, ear-mite treatment, and off-label parasite protocols do not share one interchangeable dose, route, or schedule.

The formulation must be selected before any volume can be calculated. Otic products, cat-specific preventives, injectable solutions, and concentrated horse or cattle products are not substitutes for one another. A small decimal or dilution error can be clinically important in a cat.

Use the calculator only to understand how the recorded 0.2 mg/kg value scales with weight. Do not use it to choose an indication, convert a large-animal product, or decide when to repeat treatment.

How to Give Ivermectin to Your Cat

Ivermectin administration in cats varies by indication, route, and formulation. Use only the exact cat-specific or compounded product supplied or identified by the prescribing veterinarian, and follow its label. Never convert, dilute, or measure a large-animal horse or cattle formulation at home; concentration errors can be dangerous in cats.

It is generally recommended to give Ivermectin with food to help reduce stomach upset. It may interact with Spinosad (increased ivermectin toxicity risk), Ketoconazole and other P-glycoprotein inhibitors (increased ivermectin levels), Other macrocyclic lactones (additive toxicity), and Benzodiazepines (may mask early neurotoxicity signs).

Side Effects and Safety

Common side effects include Transient lethargy, Decreased appetite, Drooling (if given orally and tastes the solution), and Mild diarrhea. More serious side effects can occur, such as Neurotoxicity (ataxia, tremors, blindness, seizures, coma), Hypersalivation and vomiting (early toxicity sign), Death (at toxic doses), and Severe allergic reaction.

Cautions · 12

When Heartgard should be used with caution or avoided

Some cats should not take Heartgard, or need a different dose and closer monitoring. Tell your veterinarian about your pet's full health history and every other medication or supplement they take before giving Heartgard.

  • Kittens under 6 weeks of age
  • Severely debilitated or underweight cats
  • Concurrent use with other macrocyclic lactones without vet guidance
  • Cats with known ivermectin sensitivity

Interactions · 13

Heartgard drug interactions

Heartgard can interact with other drugs. This list is not complete — always give your veterinarian a full list of your cat's medications and supplements.

Spinosad (increased ivermectin toxicity risk)
Ketoconazole and other P-glycoprotein inhibitors (increased ivermectin levels)
Other macrocyclic lactones (additive toxicity)
Benzodiazepines (may mask early neurotoxicity signs)

Calculator Limits · 14

When not to use this calculator

This calculator gives a general educational estimate for a healthy adult cat at a known weight. Do not rely on it in these situations — talk to your veterinarian instead:

  • In an emergency, or after accidental ingestion or a suspected overdose
  • For pregnant or nursing pets
  • For very young or very old cats
  • For pets with liver disease, kidney disease, or another chronic illness
  • For pets taking several medications at once
  • When you are not sure of your cat's current, accurate weight
  • For combination products that contain additional active ingredients

Overdose · 15

Suspected overdose: what to do

If you think your cat had too much Heartgard, or swallowed any medication by accident, act right away. Do not wait for symptoms to appear.

  • Call your veterinarian or the nearest emergency animal hospital.
  • ASPCA Animal Poison Control Center: (888) 426-4435
  • Pet Poison Helpline: (855) 764-7661

A consultation fee may apply to the poison hotlines. Have the medication packaging ready, and note how much your pet may have taken and when. Do not try to make your pet vomit unless a veterinarian tells you to.

When to Call the Vet

If your cat experiences any of the following, contact your veterinarian or an emergency clinic immediately:

Frequently Asked Questions

Frequently Asked · 07

Questions about this medication

Is ivermectin safe for cats?
Ivermectin can be safe for cats when used at the correct dose, but cats have a narrower safety margin than dogs. The heartworm prevention dose (0.024 mg/kg monthly) is very safe. Higher doses used for mange or ear mites (0.2-0.4 mg/kg) carry more risk and should only be administered by or under the direct supervision of a veterinarian. Never use ivermectin products labeled for large animals (cattle/horses) on cats, as the concentration makes accurate dosing nearly impossible and overdose is common.
Can ivermectin treat ear mites in cats?
Yes, ivermectin is very effective against ear mites (Otodectes cynotis) in cats. It can be given as a subcutaneous injection (0.2-0.4 mg/kg), applied topically in the ear canal, or given orally. A single treatment often resolves the infestation, though a second dose 2 weeks later may be recommended to kill newly hatched mites. Your vet will determine the best route of administration for your cat.
What are the signs of ivermectin toxicity in cats?
Signs of ivermectin toxicity include excessive drooling, vomiting, wobbliness (ataxia), tremors, dilated pupils, blindness, disorientation, inability to stand, seizures, and in severe cases, coma and death. Toxicity typically occurs within 4-12 hours of an overdose. If you suspect your cat has received too much ivermectin, seek immediate emergency veterinary care. There is no specific antidote, but supportive care (IV fluids, anti-seizure medication) can be life-saving.
How does ivermectin for cats differ from the dog version?
Cats generally have a narrower safety margin with ivermectin than dogs. The heartworm prevention dose is similar (0.024 mg/kg), but cats are more sensitive to higher therapeutic doses. Cat-specific products are formulated at appropriate concentrations. Dog-specific chewable heartworm preventatives should not be given to cats, as the formulation and flavorings differ. Always use cat-labeled ivermectin products.
Can I use horse ivermectin paste on my cat?
NEVER use horse or cattle ivermectin products on cats. These products are formulated at extremely high concentrations (1.87% paste, 1% injectable) designed for animals weighing hundreds of kilograms. It is virtually impossible to accurately measure a safe cat dose from these products, and even a tiny error can deliver a fatal overdose. Always use veterinary-prescribed, cat-appropriate ivermectin formulations.

Use This Guide Safely · 08

What weight alone cannot tell you

The calculator performs one narrow job: it multiplies your cat's weight by the lower, standard, and upper mg/kg values recorded for Heartgard. It cannot decide whether this drug, indication, formulation, or schedule is appropriate for an individual animal.

Context in this medication record

Commonly listed uses
Ear mite treatment (Otodectes cynotis), Heartworm prevention, Intestinal parasite treatment, Demodectic mange (off-label), Notoedric mange (off-label)
Recorded forms
Injectable solution (used orally or by injection), Topical (otic), Oral paste
Reference timing
Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention; onset 4-8 hours; duration Varies by parasite; heartworm prevention lasts approximately 30 days

Individual checks a calculator cannot perform

  • Confirm the diagnosis and the reason this medication is being considered.
  • Match the exact product, concentration, route, and whether a tablet may be split.
  • Account for age, pregnancy, organ function, genetics, allergies, and prior reactions.
  • Review every prescription, over-the-counter product, and supplement your pet takes.

Recorded cautions

Kittens under 6 weeks of age; Severely debilitated or underweight cats; Concurrent use with other macrocyclic lactones without vet guidance; Cats with known ivermectin sensitivity.

Recorded interactions

Spinosad (increased ivermectin toxicity risk); Ketoconazole and other P-glycoprotein inhibitors (increased ivermectin levels); Other macrocyclic lactones (additive toxicity); Benzodiazepines (may mask early neurotoxicity signs).

These lists reproduce the structured record used by this page and may not be exhaustive. Show your veterinarian the product label and your cat's complete medication list before acting on a number.

For Dogs

Looking for Ivermectin dosage for dogs?

View the Ivermectin dosage chart and calculator for dogs.

Related · 08

Related medications for cats

Sources · 09

Sources & references

The structured medication record behind this page names the references below. The links open the publisher or official resource; they do not turn this page into a prescription for an individual animal.

Source names are shown at the record level; passage-level page and label citations are still being added. Read our methodology and limitations.

Transparency · 11

How this page was made

This page's structured medication record includes Plumb's Veterinary Drug Handbook among its source names. PetDosageChart applies the record's mg/kg values to the entered weight and presents the arithmetic result. A source record is not the same as an individualized prescription or an independent clinical review.

Sources cited
  • Plumb's Veterinary Drug Handbook
  • Merck Veterinary Manual
Calculator formula
Doses scale linearly from a standard basis of 0.2 mg per kg (0.09 mg per lb) of body weight, given Single dose for ear mites (may repeat in 2 weeks); monthly for heartworm prevention. The calculator multiplies that basis by your cat's weight and shows an arithmetic comparison with recorded tablet sizes. That comparison does not determine whether a tablet is scored, splittable, or appropriate for your pet.
Editorial owner
Prepared and maintained by the PetDosageChart editorial team, a software-led publisher and not a veterinary practice.
DVM review status
Not independently DVM-reviewed. A named reviewer and review date appear here only after a confirmed review.

More on our methodology and editorial process — how we source, calculate, and review cats dosage data.

Safety · 10

More resources