Fluoroquinolone antibiotic · For Dogs
How much Enrofloxacin (Baytril) can I give my dog?
Standard Enrofloxacin dose for dogs is 10 mg per kg (4.54 mg per lb), given Once daily. Use the calculator below for your dog's exact weight, or jump to the weight-by-weight chart.
- Onset
- 1-2 hours
- Duration
- 24 hours
- Class
- Fluoroquinolone antibiotic
Calculator estimate from Plumb’s Veterinary Drug Handbook. Not yet vet-reviewed — see our methodology .
This dosage information is for educational purposes only. Always consult your veterinarian before giving any medication to your pet. Dosages may vary based on your pet's health conditions, other medications, and individual factors.
Content reviewed by licensed veterinarians. Sourced from Plumb's Veterinary Drug Handbook and the Merck Veterinary Manual.
Dosage Calculator · 01
Enter your dog's weight
By Weight
Baytril dose by dog weight
Pick your dog's weight to jump to a dedicated page with the dose, frequency, safety notes, and FAQ for that size.
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Dosage Chart · 02
Baytril dosage for dogs by weight
Scroll sideways to see full table
| Weight | Low Dose | Standard | Max Safe | Frequency |
|---|---|---|---|---|
| 5 lbs (2.3 kg) | 11.5mg | 23mg (22.7mg tablet) | 46mg (2 × 22.7mg) | Once daily |
| 10 lbs (4.5 kg) | 22.5mg (22.7mg tablet) | 45mg (2 × 22.7mg) | 90mg (4 × 22.7mg) | Once daily |
| 15 lbs (6.8 kg) | 34mg | 68mg (3 × 22.7mg) | 136mg (6 × 22.7mg) | Once daily |
| 20 lbs (9.1 kg) | 45.5mg (2 × 22.7mg) | 91mg (4 × 22.7mg) | 182mg (8 × 22.7mg) | Once daily |
| 25 lbs (11.3 kg) | 56.5mg | 113mg (5 × 22.7mg) | 226mg (10 × 22.7mg) | Once daily |
| 30 lbs (13.6 kg) | 68mg (3 × 22.7mg) | 136mg (6 × 22.7mg) | 272mg (12 × 22.7mg) | Once daily |
| 40 lbs (18.1 kg) | 90.5mg (4 × 22.7mg) | 181mg (8 × 22.7mg) | 362mg (16 × 22.7mg) | Once daily |
| 50 lbs (22.7 kg) | 113.5mg (5 × 22.7mg) | 227mg (10 × 22.7mg) | 454mg (20 × 22.7mg) | Once daily |
| 60 lbs (27.2 kg) | 136mg (6 × 22.7mg) | 272mg (12 × 22.7mg) | 544mg (24 × 22.7mg) | Once daily |
| 70 lbs (31.7 kg) | 158.5mg (7 × 22.7mg) | 317mg (14 × 22.7mg) | 634mg (28 × 22.7mg) | Once daily |
| 80 lbs (36.3 kg) | 181.5mg (8 × 22.7mg) | 363mg (16 × 22.7mg) | 726mg (32 × 22.7mg) | Once daily |
| 90 lbs (40.8 kg) | 204mg (9 × 22.7mg) | 408mg (18 × 22.7mg) | 816mg (36 × 22.7mg) | Once daily |
| 100 lbs (45.4 kg) | 227mg (10 × 22.7mg) | 454mg (20 × 22.7mg) | 908mg (40 × 22.7mg) | Once daily |
| 120 lbs (54.4 kg) | 272mg (12 × 22.7mg) | 544mg (24 × 22.7mg) | 1088mg (48 × 22.7mg) | Once daily |
| 150 lbs (68 kg) | 340mg (15 × 22.7mg) | 680mg (30 × 22.7mg) | 1360mg (60 × 22.7mg) | Once daily |
Common Uses · 03
What is Baytril (Enrofloxacin) used for in dogs?
Administration · 04
How to give Baytril to your dog
Give enrofloxacin tablets by mouth once daily with food. Do not give within 2 hours of antacids, sucralfate, or calcium/iron supplements as they block absorption. Ensure your dog has access to plenty of fresh water to prevent crystalluria. Complete the entire prescribed course — stopping early promotes antibiotic resistance. Do NOT use in puppies still growing (under 12-18 months). Tablets can be hidden in food or a pill pocket.
Available Forms
Tablet, Injectable, Oral suspension
Give with Food?
Yes — give with food
Side Effects · 05
Side effects of Baytril in dogs
Common side effects
Serious side effects — call your vet
- Cartilage damage in growing puppies
- Seizures
- Crystalluria
- Retinal degeneration (cats — rare in dogs)
- Tendon damage
Emergency · 06
When to call the vet
Call your vet immediately if your dog shows any of these signs:
- Joint swelling, lameness, or difficulty walking
- Seizures, tremors, or disorientation
- Blood in urine or difficulty urinating
- Severe vomiting or diarrhea that prevents keeping the medication down
- Skin rash or signs of allergic reaction
For Cats
Looking for Enrofloxacin dosage for cats?
View the Enrofloxacin dosage chart and calculator for cats.
Related · 08
Related medications for dogs
Sources · 09
Sources & references
The dosage information on this page is compiled from the following veterinary and pharmaceutical references:
- Plumb's Veterinary Drug Handbook — the standard veterinary pharmacology reference used by veterinarians worldwide.
- Merck Veterinary Manual — a trusted, peer-reviewed resource for veterinary professionals and pet owners.
- DailyMed (FDA Drug Labels) — official FDA-approved drug labeling and prescribing information for Enrofloxacin.
Read more about our methodology and how we calculate dosages.
Transparency · 11
How this page was made
Sourced from Plumb's Veterinary Drug Handbook, the reference used in US vet schools. Every dose, frequency, and tablet count on this page is generated from that data, then checked against the published references below.
- Sources cited
-
- Plumb's Veterinary Drug Handbook
- Merck Veterinary Manual
- Calculator formula
- Doses scale linearly from a standard basis of 10 mg per kg (4.54 mg per lb) of body weight, given Once daily. The calculator multiplies that basis by your dog's weight and rounds to the closest available tablet size.
- Last-reviewed status
- Automated from Plumb’s, not yet vet-reviewed.
More on our methodology and editorial process — how we source, calculate, and review dogs dosage data.
Frequently Asked · 07
Questions about this medication
Why can't growing puppies take enrofloxacin?
Should enrofloxacin be given with food?
How long is a typical course of enrofloxacin?
Is enrofloxacin a strong antibiotic?
Can enrofloxacin cause seizures?
Safety · 10
More resources
- Pet Medication Safety Hub — What's safe, what's dangerous, and emergency signs
- How we calculate dosages — Our sources, math, and review process
- Printable emergency checklist — One-page reference for your fridge or first aid kit