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PetDosageChart

Amoxil (Amoxicillin) Dosage for Dogs

Antibiotic (Penicillin) ⏱ Onset: 1-2 hours ⏳ Duration: 8-12 hours

This dosage information is for educational purposes only. Always consult your veterinarian before giving any medication to your pet. Dosages may vary based on your pet's health conditions, other medications, and individual factors.

Content reviewed by licensed veterinarians. This information is sourced from veterinary drug references including Plumb's Veterinary Drug Handbook and the Merck Veterinary Manual.

Dosage Calculator

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Amoxil Dosage Chart for Dogs by Weight

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Weight Low Dose Standard Dose Max Dose Frequency
5 lbs (2.3 kg) 11.5mg 23mg 57.5mg (50mg tablet) every 8-12 hours
10 lbs (4.5 kg) 22.5mg 45mg (50mg tablet) 112.5mg every 8-12 hours
15 lbs (6.8 kg) 34mg 68mg 170mg every 8-12 hours
20 lbs (9.1 kg) 45.5mg (50mg tablet) 91mg (2 × 50mg) 227.5mg every 8-12 hours
25 lbs (11.3 kg) 56.5mg (50mg tablet) 113mg 282.5mg every 8-12 hours
30 lbs (13.6 kg) 68mg 136mg 340mg (7 × 50mg) every 8-12 hours
40 lbs (18.1 kg) 90.5mg (2 × 50mg) 181mg 452.5mg (9 × 50mg) every 8-12 hours
50 lbs (22.7 kg) 113.5mg 227mg 567.5mg every 8-12 hours
60 lbs (27.2 kg) 136mg 272mg 680mg every 8-12 hours
70 lbs (31.7 kg) 158.5mg (3 × 50mg) 317mg 792.5mg (16 × 50mg) every 8-12 hours
80 lbs (36.3 kg) 181.5mg 363mg 907.5mg (18 × 50mg) every 8-12 hours
90 lbs (40.8 kg) 204mg (4 × 50mg) 408mg (8 × 50mg) 1020mg every 8-12 hours
100 lbs (45.4 kg) 227mg 454mg (9 × 50mg) 1135mg every 8-12 hours
120 lbs (54.4 kg) 272mg 544mg (11 × 50mg) 1360mg (27 × 50mg) every 8-12 hours
150 lbs (68 kg) 340mg (7 × 50mg) 680mg 1700mg (34 × 50mg) every 8-12 hours

What is Amoxil (Amoxicillin) used for in dogs?

bacterial infections skin infections urinary tract infections respiratory infections dental infections

How to give Amoxil to your dog

Amoxicillin can be given with or without food, but giving with food may reduce stomach upset. Always complete the full course of antibiotics as prescribed, even if your dog appears to feel better before the medication is finished. Stopping early can lead to antibiotic resistance.

Available Forms

tablet, capsule, liquid suspension

Give with Food?

Yes — give with food

Side effects of Amoxil in dogs

Common side effects

diarrhea
nausea
vomiting
decreased appetite

Serious side effects

  • allergic reaction (facial swelling, hives)
  • severe diarrhea
  • difficulty breathing
  • seizures (rare, at very high doses)

When to call the vet

Call your vet immediately if your dog shows any of these signs:

  • Signs of allergic reaction (facial swelling, hives, difficulty breathing)
  • Severe or bloody diarrhea
  • Vomiting persists after multiple doses
  • No improvement after 48-72 hours of treatment
  • Rash or skin irritation develops

Related Medications for Dogs

Fluoroquinolone antibiotic

Baytril

Enrofloxacin

For Urinary tract infections

View dosage chart
Antibiotic (Tetracycline)

Vibramycin

Doxycycline

For tick-borne diseases (Lyme, ehrlichiosis)

View dosage chart
Antibiotic / Antiprotozoal

Flagyl

Metronidazole

For diarrhea

View dosage chart
Antibiotic (Cephalosporin)

Keflex

Cephalexin

For skin infections (pyoderma)

View dosage chart

Sources & References

The dosage information on this page is compiled from the following veterinary and pharmaceutical references:

  • Plumb's Veterinary Drug Handbook — the standard veterinary pharmacology reference used by veterinarians worldwide.
  • Merck Veterinary Manual — a trusted, peer-reviewed resource for veterinary professionals and pet owners.
  • DailyMed (FDA Drug Labels) — official FDA-approved drug labeling and prescribing information for Amoxicillin.

Frequently Asked Questions

Can I give my dog human amoxicillin?
While the active ingredient is the same, you should only give your dog amoxicillin prescribed by a veterinarian. Human formulations may contain different doses or inactive ingredients. Your vet needs to determine the correct dose and duration based on the type and severity of infection.
How much amoxicillin do I give my dog?
The typical dose is 5-10 mg per kilogram of body weight, given every 8-12 hours. For more serious infections, your vet may prescribe up to 25 mg/kg. The dose depends on the type and severity of infection, so always follow your vet's prescription.
How long does amoxicillin take to work in dogs?
Amoxicillin begins fighting bacteria within 1-2 hours, but visible improvement in symptoms usually takes 2-3 days. It's crucial to complete the entire prescribed course (typically 7-14 days) even if your dog seems better, to fully eliminate the infection and prevent resistance.
What are the side effects of amoxicillin in dogs?
The most common side effects are gastrointestinal, including diarrhea, nausea, and vomiting. These are usually mild. Serious allergic reactions (facial swelling, difficulty breathing) are rare but require immediate emergency care. Probiotics may help reduce digestive side effects.

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