Antiparasitic combination · For Dogs · 100 lb
How much Trifexis for a 100 lb dog?
A 100 lb dog (45.4 kg) should receive approximately 1360.5 mg of Trifexis per dose, given once monthly.
This dosage information is for educational purposes only. Always consult your veterinarian before giving any medication to your pet. Dosages may vary based on your pet's health conditions, other medications, and individual factors.
Content reviewed by licensed veterinarians. Sourced from Plumb's Veterinary Drug Handbook and the Merck Veterinary Manual.
Dosage · 100 lb dog
Trifexis dose for a 100 lb dog
Low Dose
1360.5
mg
Standard
1360.5
mg
Max Safe
2721.1
mg
Frequency
once monthly
Weight in kg
45.4 kg
Always confirm with your veterinarian before administering medication. These calculations are estimates based on published veterinary pharmacology references.
Other Weights
Trifexis for a different size dog
FAQ · 100 lb dog
Questions about Trifexis for a 100 lb dog
How much Trifexis for a 100 lb dog?
What is the safe dose range of Trifexis for a 100 lb dog?
How often can I give Trifexis to a 100 lb dog?
Need a different weight?
Use the calculator on the main Trifexis page for any exact weight, or read the full dosage chart and safety information.
Full Trifexis dosage guide →Sources · 09
Sources & references
The dosage information on this page is compiled from the following veterinary and pharmaceutical references:
- Plumb's Veterinary Drug Handbook — the standard veterinary pharmacology reference used by veterinarians worldwide.
- Merck Veterinary Manual — a trusted, peer-reviewed resource for veterinary professionals and pet owners.
- DailyMed (FDA Drug Labels) — official FDA-approved drug labeling and prescribing information for Spinosad / Milbemycin Oxime.
Read more about our methodology and how we calculate dosages.