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PetDosageChart

Antihistamine (first-generation) · For Dogs

Atarax dosage reference for dogs (Hydroxyzine)

This page's standard weight-based reference is 2 mg per kg (0.91 mg per lb), with every 8-12 hours recorded as the reference frequency. Use the calculator to see the arithmetic for your dog's weight, then confirm the indication, product, and actual dose with a veterinarian.

Onset
30-60 minutes
Duration
8-12 hours
Class
Antihistamine (first-generation)

Weight-based calculator estimate from the references listed on this page. This page has not been independently DVM-reviewed — see our methodology .

This information is for educational purposes only. Always consult your veterinarian before giving medication to your pet. Do not use this calculator for emergencies, overdoses, pregnancy, very young animals, very old animals, pets with liver/kidney disease, or pets taking multiple medications.

Each medication page lists the references recorded for its data. The calculator math and editorial presentation are maintained by PetDosageChart; a page is independently DVM-reviewed only when a named reviewer byline appears. See our methodology and limitations.

Hydroxyzine (often known by brand names such as Atarax and Vistaril) is an antihistamine (first-generation) commonly used in veterinary medicine for allergies, itching, anxiety, and atopic dermatitis. Understanding the correct dosage, administration, and potential side effects of Hydroxyzine is critical for your dog’s safety and well-being.

A typical Hydroxyzine dose for dogs is around 2 mg/kg every 8-12 hours, within a usual range of 1-2 mg/kg. Available forms include tablet, capsule, and liquid.

Calculator Warning: Use this only as an educational estimate. Your veterinarian may prescribe a different dose based on your pet’s condition, age, weight, other medications, and medical history.

Hydroxyzine Dosage Calculator for Dogs

Enter your dog’s weight below to estimate the Hydroxyzine dose from the 2 mg/kg guideline. Your veterinarian may adjust it for your dog’s age, condition, and other medications, so treat the result as an educational starting point, not a prescription.

Dosage Calculator · 01

Enter your dog's weight

Quick Dosage Chart

Typical Hydroxyzine amounts for common dog weights, for quick reference:

Dosage Chart · 02

Atarax weight-based reference chart for dogs

Scroll sideways to see full table

Weight Lower Reference Standard Reference Upper Reference Frequency
5 lbs (2.3 kg) 2.3 mg 4.6 mg 4.6 mg every 8-12 hours
10 lbs (4.5 kg) 4.5 mg 9.0 mg (10mg tablet) 9.0 mg (10mg tablet) every 8-12 hours
15 lbs (6.8 kg) 6.8 mg 13.6 mg 13.6 mg every 8-12 hours
20 lbs (9.1 kg) 9.1 mg (10mg tablet) 18.2 mg (2 × 10mg) 18.2 mg (2 × 10mg) every 8-12 hours
25 lbs (11.3 kg) 11.3 mg (10mg tablet) 22.6 mg 22.6 mg every 8-12 hours
30 lbs (13.6 kg) 13.6 mg 27.2 mg 27.2 mg every 8-12 hours
40 lbs (18.1 kg) 18.1 mg (2 × 10mg) 36.2 mg 36.2 mg every 8-12 hours
50 lbs (22.7 kg) 22.7 mg 45.4 mg 45.4 mg every 8-12 hours
60 lbs (27.2 kg) 27.2 mg 54.4 mg 54.4 mg every 8-12 hours
70 lbs (31.7 kg) 31.7 mg (3 × 10mg) 63.4 mg 63.4 mg every 8-12 hours
80 lbs (36.3 kg) 36.3 mg 72.6 mg 72.6 mg every 8-12 hours
90 lbs (40.8 kg) 40.8 mg (4 × 10mg) 81.6 mg (8 × 10mg) 81.6 mg (8 × 10mg) every 8-12 hours
100 lbs (45.4 kg) 45.4 mg 90.8 mg (9 × 10mg) 90.8 mg (9 × 10mg) every 8-12 hours
120 lbs (54.4 kg) 54.4 mg 108.8 mg (11 × 10mg) 108.8 mg (11 × 10mg) every 8-12 hours
150 lbs (68 kg) 68.0 mg (7 × 10mg) 136.0 mg 136.0 mg every 8-12 hours

Parenthetical tablet amounts are arithmetic comparisons only. They do not account for scoring, release type, concentration, product labeling, or whether this medication is appropriate for an individual animal.

By Weight

Atarax reference by dog weight

Choose a common weight to open its optional reference page. Use the main medication calculator for a different exact weight.

Common-weight pages are convenience views of the same educational reference, not separate medical recommendations.

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How to Give Hydroxyzine to Your Dog

Hydroxyzine can be given with or without food. It is often considered more effective than diphenhydramine (Benadryl) for dogs with atopic dermatitis. Give consistently for best allergy control. May cause drowsiness, especially in the first few days.

It is generally recommended to give Hydroxyzine with food to help reduce stomach upset. It may interact with CNS depressants, anticholinergic drugs, MAO inhibitors, and other antihistamines.

Side Effects and Safety

Common side effects include drowsiness, dry mouth, decreased appetite, and mild sedation. More serious side effects can occur, such as excessive sedation, urinary retention, tremors, and seizures (at very high doses).

Cautions · 12

When Atarax should be used with caution or avoided

Some dogs should not take Atarax, or need a different dose and closer monitoring. Tell your veterinarian about your pet's full health history and every other medication or supplement they take before giving Atarax.

  • glaucoma
  • urinary retention
  • pregnancy
  • known hypersensitivity

Interactions · 13

Atarax drug interactions

Atarax can interact with other drugs. This list is not complete — always give your veterinarian a full list of your dog's medications and supplements.

CNS depressants
anticholinergic drugs
MAO inhibitors
other antihistamines

Calculator Limits · 14

When not to use this calculator

This calculator gives a general educational estimate for a healthy adult dog at a known weight. Do not rely on it in these situations — talk to your veterinarian instead:

  • In an emergency, or after accidental ingestion or a suspected overdose
  • For pregnant or nursing pets
  • For very young or very old dogs
  • For pets with liver disease, kidney disease, or another chronic illness
  • For pets taking several medications at once
  • When you are not sure of your dog's current, accurate weight
  • For combination products that contain additional active ingredients

Overdose · 15

Suspected overdose: what to do

If you think your dog had too much Atarax, or swallowed any medication by accident, act right away. Do not wait for symptoms to appear.

  • Call your veterinarian or the nearest emergency animal hospital.
  • ASPCA Animal Poison Control Center: (888) 426-4435
  • Pet Poison Helpline: (855) 764-7661

A consultation fee may apply to the poison hotlines. Have the medication packaging ready, and note how much your pet may have taken and when. Do not try to make your pet vomit unless a veterinarian tells you to.

When to Call the Vet

If your dog experiences any of the following, contact your veterinarian or an emergency clinic immediately:

Frequently Asked Questions

Frequently Asked · 07

Questions about this medication

Is hydroxyzine better than Benadryl for dogs?
Many veterinary dermatologists consider hydroxyzine more effective than Benadryl for managing allergic skin conditions in dogs. Hydroxyzine is more potent and may provide better itch relief. However, it requires a prescription, while Benadryl is available over-the-counter.
How much hydroxyzine can I give my dog?
The typical dose is 2 mg per kilogram of body weight, given every 8-12 hours. For example, a 25 lb (11 kg) dog would receive approximately 22 mg per dose. Your vet will determine the exact dose and frequency.
Does hydroxyzine make dogs sleepy?
Yes, drowsiness is the most common side effect of hydroxyzine, as it is a first-generation antihistamine. Most dogs develop tolerance to the sedative effects within a few days. The initial drowsiness often subsides with continued use.
Can I give my dog hydroxyzine every day?
Yes, hydroxyzine is commonly prescribed for daily use in dogs with chronic allergies or atopic dermatitis. Consistent daily dosing provides the best allergy control. Your vet may adjust the dose seasonally based on allergy severity.

Use This Guide Safely · 08

What weight alone cannot tell you

The calculator performs one narrow job: it multiplies your dog's weight by the lower, standard, and upper mg/kg values recorded for Atarax. It cannot decide whether this drug, indication, formulation, or schedule is appropriate for an individual animal.

Context in this medication record

Commonly listed uses
allergies, itching, anxiety, atopic dermatitis
Recorded forms
tablet, capsule, liquid
Reference timing
every 8-12 hours; onset 30-60 minutes; duration 8-12 hours

Individual checks a calculator cannot perform

  • Confirm the diagnosis and the reason this medication is being considered.
  • Match the exact product, concentration, route, and whether a tablet may be split.
  • Account for age, pregnancy, organ function, genetics, allergies, and prior reactions.
  • Review every prescription, over-the-counter product, and supplement your pet takes.

Recorded cautions

glaucoma; urinary retention; pregnancy; known hypersensitivity.

Recorded interactions

CNS depressants; anticholinergic drugs; MAO inhibitors; other antihistamines.

These lists reproduce the structured record used by this page and may not be exhaustive. Show your veterinarian the product label and your dog's complete medication list before acting on a number.

For Cats

Looking for Atarax dosage for cats?

View the Atarax dosage chart and calculator for cats.

Related · 08

Related medications for dogs

Sources · 09

Sources & references

The structured medication record behind this page names the references below. The links open the publisher or official resource; they do not turn this page into a prescription for an individual animal.

Source names are shown at the record level; passage-level page and label citations are still being added. Read our methodology and limitations.

Transparency · 11

How this page was made

This page's structured medication record includes Plumb's Veterinary Drug Handbook among its source names. PetDosageChart applies the record's mg/kg values to the entered weight and presents the arithmetic result. A source record is not the same as an individualized prescription or an independent clinical review.

Sources cited
  • Plumb's Veterinary Drug Handbook
  • Merck Veterinary Manual
Calculator formula
Doses scale linearly from a standard basis of 2 mg per kg (0.91 mg per lb) of body weight, given every 8-12 hours. The calculator multiplies that basis by your dog's weight and shows an arithmetic comparison with recorded tablet sizes. That comparison does not determine whether a tablet is scored, splittable, or appropriate for your pet.
Editorial owner
Prepared and maintained by the PetDosageChart editorial team, a software-led publisher and not a veterinary practice.
DVM review status
Not independently DVM-reviewed. A named reviewer and review date appear here only after a confirmed review.

More on our methodology and editorial process — how we source, calculate, and review dogs dosage data.

Safety · 10

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